THIAZOLE-3-CARBOXYLIC ACID - Names and Identifiers
THIAZOLE-3-CARBOXYLIC ACID - Physico-chemical Properties
Molecular Formula | C4H3NO2S
|
Molar Mass | 129.14 |
Density | 1.525±0.06 g/cm3(Predicted) |
Melting Point | 91.6-93°C |
Boling Point | 310.6±25.0 °C(Predicted) |
Flash Point | 141.6°C |
Water Solubility | Slightly soluble in water. |
Vapor Presure | 0.000256mmHg at 25°C |
Appearance | Crystallization |
pKa | 2.95±0.10(Predicted) |
Storage Condition | -20°C |
Refractive Index | 1.617 |
MDL | MFCD02094169 |
THIAZOLE-3-CARBOXYLIC ACID - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R22 - Harmful if swallowed
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S22 - Do not breathe dust.
|
WGK Germany | 1 |
HS Code | 29349990 |
THIAZOLE-3-CARBOXYLIC ACID - Introduction
Thiazole-2-carboxylic acid is an organic compound with the chemical formula C4H3NO2S. The following is a description of the properties, uses, preparation and safety information of thiazole-2-carboxylic acid:
Nature:
-Appearance: White or almost white crystal
-Melting point: 158-160 degrees Celsius
-Solubility: Soluble in common organic solvents such as water, alcohol and ether
Use:
-Thiazole-2-carboxylic acid has a wide range of applications in the manufacture of pharmaceuticals and pesticides. It is used as a precursor for the synthesis of certain nitrothiazole drugs and as a starting material for certain methylmethionine decarboxylase inhibitors.
-It can also be used as a dye, catalyst in organic synthesis and advanced intermediate substances.
Preparation Method:
-Thiazole-2-carboxylic acid can be prepared in a variety of ways. One common method is by reacting 2-aminothiazole with methylene chloride to form thiazole-2-carboxylic acid chloride, which is then reacted with water to form thiazole-2-carboxylic acid.
Safety Information:
-Thiazole-2-carboxylic acid is generally considered safe under normal conditions of use.
-But it is an organic compound that may have a certain impact on human health. In contact with it, should avoid inhalation of dust and skin exposure. Wear appropriate protective equipment, such as gloves and goggles.
-When storing and handling thiazole-2-carboxylic acid, care should be taken to avoid contact with oxidants, strong acids and strong bases to prevent dangerous reactions.
Last Update:2024-04-09 02:00:42